Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603035 | 0.86 | KMT2A (0.56) | KMT2ATSHRTDP1L3MBTL1POLB | |
| Propane SCHEMBL11522719 | 0.81 | TSHR (0.51) | KMT2ATSHRL3MBTL1POLBMAPT | |
| SCHEMBL2762261 | 0.80 | ALDH1A1 (0.50) | KMT2ATSHRTDP1L3MBTL1POLB | |
| SCHEMBL9392368 | 0.76 | TSHR (0.41) | KMT2ATSHRTDP1ALDH1A1ADORA3 | |
| SCHEMBL6434924 | 0.75 | KDM4E (0.42) | L3MBTL1MAPTHSD17B10ALDH1A1ADORA3 | |
| SCHEMBL10618369 | 0.75 | TSHR (0.55) | KMT2ATSHRTDP1L3MBTL1POLB | |
| SCHEMBL8613623 | 0.75 | GAA (0.46) | TSHRTDP1L3MBTL1POLBCYP3A4 | |
| SCHEMBL27534116 | 0.75 | ALDH1A1 (0.44) | KMT2ATSHRTDP1L3MBTL1POLB | |
| SCHEMBL11477748 | 0.74 | ALDH1A1 (0.37) | TSHRTDP1L3MBTL1POLBCYP3A4 | |
| SCHEMBL31319103 | 0.74 | TSHR (0.46) | KMT2ATSHRTDP1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857483-A1 | Substituted aminopyridines in the treatment of glucose metabolism disorders | ELI LILLY AND COMPANY (US) | 1998-08-12 | — | — | EP | disclosed |
| US-4323570-A | HYPOTENSIVE AGENTS AND TREATING GLAUCOMA | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |