Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 6/20 | 0.53 |
| ▸ | BRAF | P15056 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | KIT | P10721 | 2/20 | 0.52 |
| ▸ | FLT1 | P17948 | 2/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | LOX | P28300 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732862 | 0.84 | MAPT (0.65) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL29497315 | 0.84 | MAPT (0.65) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL54805 | 0.84 | MAPT (0.65) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL8721730 | 0.82 | KDR (0.52) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL8721823 | 0.81 | P2RY1 (0.57) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL8721027 | 0.81 | KMO (0.60) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL8721009 | 0.80 | MAPT (0.55) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL2434328 | 0.80 | MAPT (0.56) | GAAP2RY1KDM4EALDH1A1RAB9A | |
| SCHEMBL13946066 | 0.79 | KDR (0.61) | MAPTKDRBRAFMAPK14TNNI3K | |
| SCHEMBL6944159 | 0.79 | NTRK1 (0.61) | GAAP2RY1KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | claimed |
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | disclosed |