SCHEMBL8723876

SCHEMBL8723876

c1ccc(Sc2c(Sc3ccccc3)c(Sc3ccccc3)c(Sc3ccccc3)c(Sc3ccccc3)c2Sc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.53
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MGLL Q99685 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
ALDH1A1 P00352 6/20 0.45
MAPK1 P28482 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA13 Q8N1Q1 1/20 0.45
KDM1A O60341 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.40
GAA P10253 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10348599 0.91 HPGD (0.45) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL452 0.85 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL7109540 0.85 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL28332331 0.85 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL12627642 0.84 KDM1A (0.52) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL7861798 0.82 MAOA (0.56) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL23277364 0.81 MAOA (0.62) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL6554424 0.81 HPGD (0.56) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL5417674 0.81 HPGD (0.56) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL3891151 0.81 MAOA (0.62) HPGDMAPTSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801809-A Organic light-emitting material with stepped indentation type concave micro-nano structure and application thereof 南京工业大学 2024-04-02 CN claimed
US-5730954-A Preparation comprising cavitate- or clathrate-forming host/guest complexes as contrast agent SCHERING AKTIENGESELLSCHAFT (DE) 1998-03-24 US claimed
EP-0357163-B1 AGENT CONSISTING OF HODT/GUEST COMPLEXES AS CONTRASTING AGENTS PRESENTING CAVITIES OF CLATHRATES SCHERING AKTIENGESELLSCHAFT (DE) 1992-06-03 EP claimed
EP-0357163-A1 Agent consisting of hodt/guest complexes as contrasting agents presenting cavities of clathrates SCHERING AKTIENGESELLSCHAFT (DE) 1990-03-07 EP claimed
CN-117801809-A Organic light-emitting material with stepped indentation type concave micro-nano structure and application thereof 南京工业大学 2024-04-02 CN disclosed
US-5730954-A Preparation comprising cavitate- or clathrate-forming host/guest complexes as contrast agent SCHERING AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
EP-0357163-B1 AGENT CONSISTING OF HODT/GUEST COMPLEXES AS CONTRASTING AGENTS PRESENTING CAVITIES OF CLATHRATES SCHERING AKTIENGESELLSCHAFT (DE) 1992-06-03 EP disclosed
EP-0377625-A1 PREPARATION OF DERIVATIVES The University of Glasgow, University Court (GB) 1990-07-18 EP disclosed
WO-1990001952-A1 CONTRAST PREPARATION CONSISTING OF CAVITATE- OR CLATHRATE-FORMING HOST/GUEST COMPLEXES SCHERING AG, BERLIN UND BERGKAMEN (DE) 1990-03-08 WO disclosed
EP-0357163-A1 Agent consisting of hodt/guest complexes as contrasting agents presenting cavities of clathrates SCHERING AKTIENGESELLSCHAFT (DE) 1990-03-07 EP disclosed
WO-1989001931-A1 PREPARATION OF DERIVATIVES THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 1989-03-09 WO disclosed