⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521329 | 0.78 | — | — | |
| SCHEMBL8225875 | 0.77 | — | — | |
| SCHEMBL7692952 | 0.75 | — | — | |
| SCHEMBL21816739 | 0.74 | — | — | |
| SCHEMBL720192 | 0.73 | — | — | |
| SCHEMBL27476467 | 0.73 | — | — | |
| SCHEMBL6251501 | 0.71 | — | — | |
| SCHEMBL3399847 | 0.70 | TSHR (0.37) | — | |
| SCHEMBL4445189 | 0.69 | USP2 (0.54) | — | |
| Sulfuric Acid SCHEMBL25250204 | 0.67 | CA5A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830852-A | Compositions for insulin-receptor mediated nucleic acid delivery | COBRA THERAPEUTICS, LTD. (GB) | 1998-11-03 | — | — | US | disclosed |
| EP-0873138-A2 | IMPROVED PHARMACEUTICAL COMPOSITIONS | Therexsys Limited (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0831922-A2 | IMPROVED PHARMACEUTICAL COMPOSITIONS FOR GENE THERAPY | Therexsys Limited (GB) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997022363-A2 | IMPROVED PHARMACEUTICAL COMPOSITIONS | THEREXSYS LIMITED (GB) | 1997-06-26 | — | — | WO | disclosed |
| WO-1996041606-A2 | IMPROVED PHARMACEUTICAL COMPOSITIONS FOR GENE THERAPY | THEREXSYS LIMITED (GB) | 1996-12-27 | — | — | WO | disclosed |