Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 0.49 |
| ▸ | HTR1B | P28222 | 11/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1F | P30939 | 2/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724037 | 0.89 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL8721060 | 0.88 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8723889 | 0.87 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8723870 | 0.87 | HTR1D (0.50) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL8723990 | 0.86 | HTR1D (0.50) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8721855 | 0.85 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL5312586 | 0.85 | KDR (0.42) | SMN1; SMN2 | |
| SCHEMBL8720667 | 0.85 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FHTR6 | |
| SCHEMBL30909067 | 0.84 | HTR1D (0.54) | HTR1DHTR1BHTR1AHTR1FSLC2A1 | |
| SCHEMBL8713578 | 0.82 | SLC6A4 (0.52) | HTR1DHTR1BHTR1AHTR1FRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |