Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 17/20 | 0.49 |
| ▸ | HTR1B | P28222 | 15/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1F | P30939 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720667 | 0.92 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8724231 | 0.87 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8721855 | 0.86 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL8721060 | 0.86 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL7489359 | 0.85 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8723990 | 0.84 | HTR1D (0.50) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8720833 | 0.83 | HTR1D (0.51) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8721017 | 0.83 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL30909067 | 0.82 | HTR1D (0.54) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8387183 | 0.82 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR1FSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |