Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | IL6ST | P40189 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 2/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950922 | 0.83 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL7945756 | 0.83 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL6956827 | 0.83 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL6950253 | 0.83 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL6950257 | 0.83 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL6958547 | 0.82 | CRHBP (0.38) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL7950843 | 0.82 | CRHBP (0.38) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL6956625 | 0.82 | CRHBP (0.38) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL8722000 | 0.80 | CRHBP (0.38) | CRHBPCRHR2ALDH1A1GAAHTT | |
| SCHEMBL7888208 | 0.80 | CRHBP (0.38) | CRHBPCRHR2ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |