Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722484 | 0.83 | L3MBTL1 (0.54) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8725784 | 0.83 | L3MBTL1 (0.54) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8721554 | 0.83 | L3MBTL1 (0.54) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL9642715 | 0.81 | NPC1 (0.89) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8724946 | 0.80 | NPC1 (0.56) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL9187561 | 0.79 | NPC1 (1.00) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL2304857 | 0.79 | NPC1 (0.72) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL16065406 | 0.79 | NPC1 (0.72) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8581954 | 0.79 | NPC1 (0.72) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL7972481 | 0.79 | NPC1 (0.72) | NPC1RAB9ARECQLKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800624-A | LIPOPHILIC POLYMER, HYDROPHOBIC PLASTICIZER, QUATERNARY AMMONIUM OR PHOSPHONIUM CARRIER | UNIVERSITY OF NOTRE DAME (US) | 1998-09-01 | — | — | US | disclosed |