Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151187 | 1.00 | KCNH2 (0.58) | KCNH2SIGMAR1TDP1L3MBTL1MITF | |
| SCHEMBL23014940 | 0.93 | KCNH2 (0.51) | KCNH2SIGMAR1TDP1L3MBTL1MITF | |
| SCHEMBL25590542 | 0.91 | KCNH2 (0.53) | KCNH2SIGMAR1TDP1L3MBTL1MITF | |
| SCHEMBL23015030 | 0.91 | KCNH2 (0.53) | KCNH2SIGMAR1TDP1L3MBTL1MITF | |
| SCHEMBL24811923 | 0.84 | KCNH2 (0.53) | KCNH2SIGMAR1MITFLMNAACHE | |
| SCHEMBL793588 | 0.84 | KCNH2 (0.50) | KCNH2SIGMAR1MITFLMNAACHE | |
| SCHEMBL20325128 | 0.83 | KCNH2 (0.56) | KCNH2SIGMAR1MITFLMNAMEN1 | |
| SCHEMBL6370599 | 0.81 | KCNH2 (0.50) | KCNH2SIGMAR1MITFLMNAACHE | |
| SCHEMBL1789939 | 0.81 | KCNH2 (0.50) | KCNH2SIGMAR1MITFLMNASTS | |
| SCHEMBL31573982 | 0.81 | KCNH2 (0.67) | KCNH2SIGMAR1MITFLMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800624-A | LIPOPHILIC POLYMER, HYDROPHOBIC PLASTICIZER, QUATERNARY AMMONIUM OR PHOSPHONIUM CARRIER | UNIVERSITY OF NOTRE DAME (US) | 1998-09-01 | — | — | US | disclosed |