SCHEMBL793588

SCHEMBL793588

CC(C)(C)c1ccc(CCOCCc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.50
ACHE P22303 3/20 0.48
MITF O75030 1/20 0.45
SIGMAR1 Q99720 4/20 0.44
GRIA4 P48058 1/20 0.43
APP P05067 1/20 0.43
TSHR P16473 2/20 0.42
SLC13A5 Q86YT5 2/20 0.42
ESRRG P62508 2/20 0.42
DAO P14920 1/20 0.42
TP53 P04637 1/20 0.41
ESRRB O95718 1/20 0.41
LMNA P02545 1/20 0.41
TYR P14679 1/20 0.41
BCHE P06276 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1890232 0.84 KCNH2 (0.48) KCNH2MITFSIGMAR1GRIA4APP
SCHEMBL22560520 0.84 KCNH2 (0.39) KCNH2ACHEMITFSIGMAR1GRIA4
SCHEMBL8724971 0.84 KCNH2 (0.58) KCNH2ACHEMITFSIGMAR1ESRRG
SCHEMBL30151187 0.84 KCNH2 (0.58) KCNH2ACHEMITFSIGMAR1ESRRG
SCHEMBL7456580 0.83 KCNH2 (0.59) KCNH2ACHESIGMAR1GRIA4TSHR
SCHEMBL1890230 0.83 KCNH2 (0.47) KCNH2ACHEMITFSIGMAR1GRIA4
SCHEMBL24811923 0.79 KCNH2 (0.53) KCNH2ACHEMITFSIGMAR1GRIA4
SCHEMBL25590542 0.79 KCNH2 (0.53) KCNH2ACHEMITFSIGMAR1ESRRG
SCHEMBL31573982 0.78 KCNH2 (0.67) KCNH2ACHEMITFSIGMAR1GRIA4
SCHEMBL3361817 0.78 KCNH2 (0.43) KCNH2MITFSIGMAR1GRIA4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616424-B1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2015-08-26 EP disclosed
EP-2616424-A1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2013-07-24 EP disclosed
WO-2012034930-A1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2012-03-22 WO disclosed
WO-2005066390-A2 ELECTROCHEMICAL ALKOXYLATING OXIDATIVE CARBON-CARBON BOND CLEAVAGE IN 1,2-DIPHENYLETHANE AND DERIVATIVES THEREOF ON A DIAMOND ELECTRODE BASF AKTIENGESELLSCHAFT (DE) 2005-07-21 WO disclosed