Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754365 | 0.94 | TDP1 (0.57) | TDP1ALDH1A1RAB9ANPC1MAPT | |
| Iodide SCHEMBL2073151 | 0.92 | TDP1 (0.55) | TDP1ALDH1A1RAB9ANPC1MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL23356562 | 0.85 | TDP1 (0.44) | TDP1ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL10548005 | 0.77 | TDP1 (0.51) | TDP1ALDH1A1NPC1MAPTKDM4E | |
| SCHEMBL2796338 | 0.76 | TDP1 (0.59) | TDP1ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL57166 | 0.70 | TDP1 (1.00) | TDP1ALDH1A1GAAPOLBTSHR | |
| SCHEMBL29475175 | 0.70 | TDP1 (1.00) | TDP1ALDH1A1GAAPOLBTSHR | |
| SCHEMBL8754514 | 0.69 | NQO2 (0.43) | ALDH1A1RAB9AMAPTKDM4EHTT | |
| SCHEMBL10256593 | 0.69 | TSHR (0.54) | TDP1ALDH1A1RAB9ANPC1MAPT | |
| Methyl Alcohol SCHEMBL28304524 | 0.68 | TDP1 (0.86) | TDP1ALDH1A1NPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643698-B1 | SPECTROPHOTOMETRIC METHODS FOR ASSAYING TOTAL MERCAPTANS, REDUCED GLUTATHIONE (GSH) AND MERCAPTANS OTHER THAN GSH IN AN AQUEOUS MEDIUM, REAGENTS AND KITS FOR THEIR IMPLEMENTATION | OXIS INT SA (FR) | 1997-03-05 | — | — | EP | claimed |
| US-5817520-A | USING A QUINOLINIUM INDICATOR | OXIS INTERNATIONAL S.A. (FR) | 1998-10-06 | — | — | US | disclosed |