Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725236 | 0.77 | TDP1 (0.50) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL29475175 | 0.72 | TDP1 (1.00) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL57166 | 0.72 | TDP1 (1.00) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| Methyl Alcohol SCHEMBL28304524 | 0.70 | TDP1 (0.86) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL28093598 | 0.70 | TDP1 (0.95) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL8754365 | 0.69 | TDP1 (0.57) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL2963038 | 0.69 | TDP1 (0.75) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL29643206 | 0.69 | TDP1 (0.75) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| Iodide SCHEMBL2073151 | 0.68 | TDP1 (0.55) | TDP1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL26059158 | 0.66 | TDP1 (0.69) | TDP1ALDH1A1GAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | disclosed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |