Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524732 | 0.91 | MCHR1 (0.46) | MCHR1SMN1; SMN2ALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL514092 | 0.91 | MCHR1 (0.46) | MCHR1SMN1; SMN2ALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL305722 | 0.89 | SMN1; SMN2 (0.42) | MCHR1SMN1; SMN2ALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL16908425 | 0.85 | GAA (0.45) | SMN1; SMN2ALDH1A1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL14840202 | 0.83 | MCHR1 (0.47) | MCHR1SMN1; SMN2ALDH1A1CYP2C9CYP3A4 | |
| Hexadecylamine SCHEMBL7554404 | 0.83 | MCHR1 (0.42) | MCHR1SMN1; SMN2ALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL306553 | 0.78 | SMN1; SMN2 (0.41) | MCHR1SMN1; SMN2ALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL4456402 | 0.78 | TDP1 (0.42) | ALDH1A1TDP1TSHRCA2CA12 | |
| SCHEMBL4459094 | 0.78 | TDP1 (0.42) | ALDH1A1TDP1TSHRCA2CA12 | |
| SCHEMBL3421179 | 0.77 | CA2 (0.39) | ALDH1A1CYP2C9CYP3A4CYP2C19VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800624-A | LIPOPHILIC POLYMER, HYDROPHOBIC PLASTICIZER, QUATERNARY AMMONIUM OR PHOSPHONIUM CARRIER | UNIVERSITY OF NOTRE DAME (US) | 1998-09-01 | — | — | US | disclosed |