Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49554 | 0.88 | NQO1 (0.70) | NQO1GAAKDM4ENFKB1MAPT | |
| SCHEMBL9514574 | 0.88 | NQO1 (0.70) | NQO1GAAKDM4ENFKB1MAPT | |
| SCHEMBL8721610 | 0.85 | MAPT (0.50) | GAAKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL21151 | 0.81 | — | — | |
| SCHEMBL8721616 | 0.80 | KDM4E (0.44) | GAAKDM4EMAPTTDP1L3MBTL1 | |
| SCHEMBL9479637 | 0.80 | MAPT (0.63) | NQO1GAAKDM4ENFKB1MAPT | |
| SCHEMBL3627657 | 0.80 | MAPT (0.71) | NQO1GAAKDM4ENFKB1MAPT | |
| SCHEMBL8738419 | 0.80 | NQO1 (0.58) | NQO1KDM4ENFKB1MAPTCTDSP1 | |
| SCHEMBL3440767 | 0.80 | MAPT (0.63) | NQO1GAAKDM4ENFKB1MAPT | |
| SCHEMBL11677967 | 0.79 | GAA (0.56) | NQO1GAAKDM4ENFKB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |