SCHEMBL49554

SCHEMBL49554

CCOc1ccc(Nc2ccc(OCC)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.70
KDM4E B2RXH2 3/20 0.61
NFKB1 P19838 1/20 0.61
MAPT P10636 5/20 0.61
POLB P06746 3/20 0.59
KMT2A Q03164 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
MEN1 O00255 2/20 0.59
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
SYK P43405 1/20 0.58
ALDH1A1 P00352 1/20 0.57
TSHR P16473 1/20 0.56
NPSR1 Q6W5P4 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
OPRM1 P35372 1/20 0.56
OPRD1 P41143 1/20 0.56
RAD52 P43351 1/20 0.56
KDR P35968 1/20 0.54
SLC2A1 P11166 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514574 1.00 NQO1 (0.70) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL3440767 0.91 MAPT (0.63) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL8738419 0.91 NQO1 (0.58) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL9479637 0.91 MAPT (0.63) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL3627657 0.91 MAPT (0.71) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL11201059 0.89 KDM4E (0.62) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL11558140 0.89 LTA4H (0.68) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL9638067 0.89 TSHR (0.76) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL8725864 0.88 NQO1 (0.54) NQO1KDM4ENFKB1MAPTPOLB
SCHEMBL11725570 0.86 LMNA (0.54) NQO1KDM4ENFKB1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019810-A Combinations of specific fused naphthopyran isomers 罗登斯托克有限责任公司 2024-05-10 CN claimed
EP-4240797-A1 COMBINATION OF SPECIFIC ANNELLATED NAPHTHOPYRANE ISOMERS Rodenstock GmbH (DE) 2023-09-13 EP claimed
WO-2023135127-A1 COMBINATION OF SPECIFIC ANNELLATED NAPHTHOPYRANE ISOMERS RODENSTOCK GMBH (DE) 2023-07-20 WO claimed
WO-2026090602-A1 PIGMENTED RESIN AND CATALYST COMPOSITIONS MATERIA, INC. (US) 2026-04-30 WO disclosed
EP-3110862-B1 ADHESION PROMOTER COMPOSITIONS FOR CYCLIC OLEFIN RESIN COMPOSITIONS ExxonMobil Product Solutions Company (US) 2026-04-01 EP disclosed
US-12590180-B2 Olefinic compositions comprising hydrocarbon resins ExxonMobil Product Solutions Company (US) 2026-03-31 US disclosed
EP-4683900-A2 ROMP AND THERMAL INSULATION COMPOSITIONS AND MATERIALS AND USE THEREOF Materia, Inc. (US) 2026-01-28 EP disclosed
WO-2025245037-A1 CYCLIC OLEFIN COMPOSITIONS, ROMP COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF MATERIA, INC. (US) 2025-11-27 WO disclosed
EP-2970522-B1 IN-MOLD COATING OF ROMP POLYMERS MATERIA INC (US) 2025-05-21 EP disclosed
US-20250136744-A1 HYBRID OLEFINIC COMPOSITIONS COMPRISING RESIN COMPOSITIONS POLYMERIZABLE BY ADDITION OR CONDENSATION POLYMERIZATION REACTIONS ExxonMobil Product Solutions Company 2025-05-01 US disclosed
EP-3013886-B1 THERMAL INSULATION MATERIA INC (US) 2025-03-26 EP disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP disclosed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO disclosed
US-5346769-A Electrical laminating applications, printed circuits SHELL OIL COMPANY (US) 1994-09-13 US disclosed
EP-0183191-B1 THIENYLTHIAZOLE COMPOUNDS Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1989-05-10 EP disclosed
US-4720493-A Thienylthiazole compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1988-01-19 US disclosed
EP-0183191-A1 Thienylthiazole compounds Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-06-04 EP disclosed
US-4144260-A Production of aluminum salts of N-nitroso-N-alkyl-hydroxylamines BASF AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4082749-A FROM CARBOXAMIDES AND ALKALI METAL HYPOCHLORITE, CATALYST BASF AKTIENGESELLSCHAFT (DT) 1978-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590180-B2 Olefinic compositions comprising hydrocarbon resins RAD51, COG2, HRH2 NQO1 1433/4885KDM4E 2141/4885NFKB1 3885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.