Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721936 | 0.92 | KCNQ3 (0.47) | GRM4NTRK1KDRFLT1FLT4 | |
| SCHEMBL8721207 | 0.83 | NTRK1 (0.63) | NTRK1TLR8LOXLOXL2GAA | |
| SCHEMBL10134862 | 0.81 | POLB (0.51) | IGF1RKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL8721048 | 0.80 | GAA (0.59) | NTRK1KDRTLR8ABL1GAA | |
| SCHEMBL6944159 | 0.77 | NTRK1 (0.61) | NTRK1KDRTLR8GAA | |
| SCHEMBL8723965 | 0.76 | NTRK1 (0.63) | NTRK1KDRTLR8GAA | |
| SCHEMBL8720589 | 0.75 | NTRK1 (0.58) | NTRK1KDRTLR8GAA | |
| SCHEMBL8720588 | 0.74 | P2RY1 (0.56) | NTRK1TLR8GAA | |
| SCHEMBL8725888 | 0.73 | CBLB (0.45) | NTRK1KDRIGF1RSCN2ASCN10A | |
| SCHEMBL27682749 | 0.72 | ALDH1A1 (0.52) | GRM4CDK8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | claimed |