Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | PNP | P00491 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8723782 | 0.99 | KMT2A (0.52) | KMT2AGAAPNPNPC1ALDH1A1 | |
| Isobutanol SCHEMBL10444099 | 0.90 | KMT2A (0.45) | KMT2AGAAPNPNPC1ALDH1A1 | |
| SCHEMBL8600371 | 0.84 | TNKS2 (0.53) | ALDH1A1TLR7TLR8 | |
| SCHEMBL21949819 | 0.83 | PKM (0.49) | TLR7PKMTLR8 | |
| SCHEMBL9036182 | 0.81 | TLR7 (0.52) | GAAALDH1A1TLR7KDM4ETLR8 | |
| SCHEMBL18268482 | 0.80 | TLR7 (0.41) | RAB9ATLR7TLR8 | |
| SCHEMBL22814310 | 0.80 | PIM1 (0.45) | KMT2ATLR7TLR8 | |
| SCHEMBL9038851 | 0.79 | PARP1 (0.57) | TLR7TLR8 | |
| SCHEMBL19475356 | 0.79 | RAD52 (0.43) | TLR7TLR8 | |
| SCHEMBL5335436 | 0.78 | TLR7 (0.50) | ALDH1A1TLR7KDM4ETDP1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385630-B1 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES INC (US) | 1996-11-27 | — | — | EP | claimed |
| EP-0385630-A2 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES, INC. (US) | 1990-09-05 | — | — | EP | claimed |
| US-5756747-A | 1H-imidazo 4,5-c!quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0385630-B1 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES INC (US) | 1996-11-27 | — | — | EP | disclosed |
| EP-0389302-B1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES INC (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5037986-A | Olefinic 1H-imidazo[4,5-c]quinolin-4-amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0389302-A1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| EP-0385630-A2 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES, INC. (US) | 1990-09-05 | — | — | EP | disclosed |