Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | TYMS | P04818 | 7/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726314 | 0.96 | CA2 (0.49) | CA2CA1TYMSMRGPRX4CA12 | |
| SCHEMBL2638442 | 0.93 | TYMS (0.48) | CA2CA1TYMSCA12CA9 | |
| SCHEMBL8721870 | 0.89 | CA2 (0.53) | CA2CA1TYMSMRGPRX4CA12 | |
| SCHEMBL2638361 | 0.89 | TYMS (0.51) | CA2CA1TYMSCA12CA9 | |
| SCHEMBL6510354 | 0.86 | CA2 (0.53) | CA2CA1TYMSCA12CA9 | |
| SCHEMBL2638767 | 0.81 | TYMS (0.53) | CA2CA1TYMSCA12CA9 | |
| SCHEMBL28905229 | 0.81 | TYMS (0.53) | CA2CA1TYMSCA12CA9 | |
| SCHEMBL13338129 | 0.78 | CA2 (0.52) | CA2CA1TYMSCA12CA9 | |
| SCHEMBL887827 | 0.78 | CA2 (0.52) | CA2CA1TYMSCA12CA9 | |
| SCHEMBL14497757 | 0.78 | CA2 (0.52) | CA2CA1TYMSCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696270-B1 | 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 1998-11-04 | — | — | EP | claimed |