Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MYOC | Q99972 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26936532 | 0.83 | MEN1 (0.65) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL4743116 | 0.83 | MEN1 (0.55) | MEN1KMT2ASRD5A2KDM4EMAPT | |
| SCHEMBL16343154 | 0.83 | HTT (0.55) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL3133551 | 0.82 | MEN1 (0.68) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL3911770 | 0.82 | MEN1 (0.68) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL264541 | 0.81 | MEN1 (1.00) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL17185272 | 0.80 | SRD5A2 (0.61) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL28561063 | 0.79 | SRD5A2 (0.90) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL6623045 | 0.79 | SRD5A2 (0.90) | MEN1KMT2ASRD5A2KDM4ETDP1 | |
| SCHEMBL8722124 | 0.79 | TSHR (0.52) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |