Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728027 | 0.84 | SRD5A2 (0.54) | TSHRTPMTMAPTKMT2AMEN1 | |
| SCHEMBL10817393 | 0.79 | ALDH1A1 (0.56) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8726219 | 0.79 | MEN1 (0.68) | TSHRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL223878 | 0.78 | TTR (0.64) | TSHRTPMTMAPTKMT2AMEN1 | |
| SCHEMBL29753668 | 0.78 | TTR (0.64) | TSHRTPMTMAPTKMT2AMEN1 | |
| SCHEMBL10756062 | 0.77 | TPMT (0.72) | TSHRTPMTMAPTKMT2AMEN1 | |
| SCHEMBL4690580 | 0.76 | MEN1 (0.49) | TSHRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL31118326 | 0.76 | ALDH1A1 (0.47) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8184777 | 0.76 | TPMT (0.62) | TSHRTPMTMAPTKMT2AMEN1 | |
| SCHEMBL16792372 | 0.76 | ALDH1A1 (0.57) | MAPTKMT2AMEN1TTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |