Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721823 | 0.84 | P2RY1 (0.57) | NPY5RP2RY1TLR8TLR7RAB9A | |
| SCHEMBL54805 | 0.81 | MAPT (0.65) | NPY5RP2RY1TLR8TLR7RAB9A | |
| SCHEMBL29732862 | 0.81 | MAPT (0.65) | NPY5RP2RY1TLR8TLR7RAB9A | |
| SCHEMBL29497315 | 0.81 | MAPT (0.65) | NPY5RP2RY1TLR8TLR7RAB9A | |
| SCHEMBL6944159 | 0.78 | NTRK1 (0.61) | NPY5RP2RY1TLR8TLR7RAB9A | |
| SCHEMBL9795455 | 0.77 | P2RY1 (0.56) | NPY5RP2RY1TLR8TLR7RAB9A | |
| SCHEMBL8723508 | 0.76 | GAA (0.58) | P2RY1TLR8TLR7RAB9AGAA | |
| SCHEMBL20894934 | 0.76 | GAA (0.57) | P2RY1TLR8TLR7RAB9AGAA | |
| SCHEMBL7605482 | 0.76 | MAPT (0.67) | P2RY1TLR8TLR7RAB9AGAA | |
| SCHEMBL8721730 | 0.75 | KDR (0.52) | NPY5RP2RY1TLR8TLR7RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759956-A | PYRAZINE CARBOXAMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0700391-A1 | HERBICIDAL COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027974-A1 | HERBICIDAL COMPOUNDS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-12-08 | — | — | WO | disclosed |