Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747293 | 0.89 | TDP1 (0.48) | TDP1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL21402172 | 0.86 | — | — | |
| SCHEMBL28726197 | 0.82 | — | — | |
| SCHEMBL9825250 | 0.82 | POLB (0.53) | TDP1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL1386940 | 0.80 | POLB (0.52) | TDP1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL18608234 | 0.77 | TDP1 (0.48) | TDP1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL20908426 | 0.77 | MAPT (0.48) | TDP1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL3258927 | 0.77 | POLB (0.48) | TDP1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL8372303 | 0.77 | CHRM5 (0.52) | TDP1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL3438539 | 0.75 | MAPT (0.61) | TDP1POLBMAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5766556-A | SUITABLE ENVIRONMENT FOR SIMULTANEOUS SYNTHESIS OF ORGANIC COMPOUNDS, INORGANIC COMPOUNDS AND ORGANOMETALLIC COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0216299-A1 | Quinoxaline derivatives, method for their preparartion and their use to protect cultivated plants against phytotoxical reaction of herbicides | BASF Aktiengesellschaft (DE) | 1987-04-01 | — | — | EP | disclosed |