Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
| ▸ | HLCS | P50747 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441571 | 0.93 | TDP1 (0.71) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL23514610 | 0.89 | TDP1 (0.69) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL3306968 | 0.89 | TDP1 (0.69) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL10063250 | 0.89 | TDP1 (0.69) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL12578920 | 0.88 | TDP1 (0.71) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL14255199 | 0.88 | TDP1 (0.71) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL12650837 | 0.88 | TDP1 (0.71) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL7902281 | 0.88 | F2 (0.69) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL18779801 | 0.87 | TDP1 (0.78) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL9412852 | 0.87 | TDP1 (0.74) | TDP1PKMMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763191-A | BINDING MATRIX | BOEHRINGER MANNHEIM GMBH (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0515615-B1 | UNIVERSAL BINDING FILM | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-04 | — | — | EP | disclosed |