Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.48 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | PGD | P52209 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723225 | 1.00 | LPAR5 (0.51) | LPAR5LPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL1834727 | 0.83 | TDP1 (0.43) | — | |
| SCHEMBL28797228 | 0.77 | TDP1 (0.42) | — | |
| SCHEMBL1286423 | 0.77 | PGK1 (0.58) | LPAR5LPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL13894007 | 0.76 | LPAR5 (0.49) | LPAR5LPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL12766757 | 0.76 | LPAR5 (0.63) | LPAR5LPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL10238867 | 0.76 | LPAR5 (0.63) | LPAR5LPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL10280030 | 0.76 | LPAR5 (0.63) | LPAR5LPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL17585751 | 0.76 | LPAR5 (0.63) | LPAR5LPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL10238872 | 0.76 | LPAR5 (0.63) | LPAR5LPAR1LPAR3LPAR4LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827831-A | Lipid nucleotide analog prodrugs for oral administration | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-10-27 | — | — | US | claimed |