SCHEMBL8726705

SCHEMBL8726705

C=CCCCOCc1ccc(C2CCC(C=C)CC2)cc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 1/20 0.33
TEAD3 Q99594 1/20 0.32
SPHK1 Q9NYA1 3/20 0.32
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8726703 1.00 HDAC2 (0.33) HDAC2TEAD3SPHK1ESR1ESR2
SCHEMBL8730945 0.96 HDAC2 (0.32) HDAC2TEAD3SPHK1ESR1
SCHEMBL8730931 0.96 HDAC2 (0.32) HDAC2TEAD3SPHK1ESR1
SCHEMBL8730472 0.96 NAAA (0.34) HDAC2TEAD3SPHK1ESR1FFAR4
SCHEMBL8730480 0.96 NAAA (0.34) HDAC2TEAD3SPHK1ESR1FFAR4
SCHEMBL8730939 0.96 HDAC2 (0.32) HDAC2TEAD3SPHK1ESR1
SCHEMBL8731302 0.94 ESR2 (0.38) HDAC2ESR1ESR2CYP3A4CYP2C9
SCHEMBL8731291 0.94 ESR2 (0.38) HDAC2ESR1ESR2CYP3A4CYP2C9
SCHEMBL8731295 0.94 ESR2 (0.38) HDAC2ESR1ESR2CYP3A4CYP2C9
SCHEMBL8732725 0.93 ESR2 (0.32) HDAC2TEAD3SPHK1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed