⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142437 | 0.82 | — | — | |
| SCHEMBL7142008 | 0.74 | NOX1 (0.38) | — | |
| SCHEMBL7148664 | 0.68 | ALOX5 (0.33) | — | |
| SCHEMBL7723528 | 0.66 | — | — | |
| SCHEMBL8457650 | 0.66 | NOX1 (0.30) | — | |
| SCHEMBL2310937 | 0.58 | NOX1 (0.46) | — | |
| SCHEMBL2582870 | 0.58 | NOX1 (0.53) | — | |
| SCHEMBL7149316 | 0.58 | KDM4E (0.39) | — | |
| SCHEMBL8965830 | 0.58 | NOX1 (0.50) | — | |
| SCHEMBL30622722 | 0.58 | NOX1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739351-A4 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS INC (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0739351-A1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995018820-A1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |