Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353881 | 0.90 | ALDH1A1 (0.47) | ALDH1A1GAATDP1ADRA2BPTGS1 | |
| SCHEMBL872064 | 0.85 | ALDH1A1 (0.56) | ALDH1A1GAATDP1ADRA2BPTGS1 | |
| SCHEMBL1341730 | 0.80 | CYP3A4 (0.48) | ALDH1A1GAATDP1CYP3A4ALOX15 | |
| SCHEMBL21693954 | 0.79 | ALDH1A1 (0.41) | ALDH1A1GAATDP1ADRA2BPTGS1 | |
| SCHEMBL3426863 | 0.77 | ALDH1A1 (0.58) | ALDH1A1GAATDP1ADRA2BPTGS1 | |
| SCHEMBL13262147 | 0.75 | ALDH1A1 (0.45) | ALDH1A1GAATDP1ADRA2BPTGS1 | |
| Acetic Acid SCHEMBL2127698 | 0.75 | ALDH1A1 (0.45) | ALDH1A1GAATDP1ADRA2BPTGS1 | |
| SCHEMBL15173401 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1GAATDP1CYP3A4ALOX15 | |
| SCHEMBL31375639 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1GAATDP1CYP3A4ALOX15 | |
| SCHEMBL871739 | 0.74 | CYP2C9 (0.58) | ALDH1A1GAATDP1ADRA2BPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619199-A2 | CYTOSOLIC FLUORESCENT ION INDICATORS | Asante Research, LLC (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040204-A2 | CYTOSOLIC FLUORESCENT ION INDICATORS | ASANTE RESEARCH, LLC (US) | 2012-03-29 | — | — | WO | disclosed |