Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22547094 | 0.81 | FABP5 (0.49) | SLC6A4SLC6A2 | |
| SCHEMBL26240846 | 0.81 | FABP5 (0.49) | SLC6A4SLC6A2 | |
| SCHEMBL27939779 | 0.81 | KDM1A (0.39) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL26318046 | 0.80 | KDM1A (0.56) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL14804306 | 0.80 | KDM1A (0.56) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL4607042 | 0.75 | GRIA4 (0.43) | KDM1AMAOBGRIA4GRIA2SLC6A4 | |
| SCHEMBL8829212 | 0.74 | KDM1A (0.51) | KDM1AKDM1B | |
| SCHEMBL8215129 | 0.74 | KDM1A (0.51) | KDM1AKDM1B | |
| SCHEMBL8726619 | 0.74 | KDM1A (0.51) | KDM1AKDM1B | |
| SCHEMBL8726273 | 0.73 | KDM1A (0.39) | KDM1AKCNH2MAOBRCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853613-A | Chiral cyclohexyl compounds | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1998-12-29 | — | — | US | disclosed |