Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726274 | 1.00 | KDM1A (0.39) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL10554340 | 0.87 | KDM1A (0.45) | KDM1AMAOBHTR2CSLC6A4SLC6A3 | |
| SCHEMBL10552265 | 0.87 | SLC6A3 (0.38) | KDM1ASLC6A3CYP2C9 | |
| SCHEMBL10554664 | 0.86 | SLC6A3 (0.40) | MAOBSLC6A3CYP2C9 | |
| SCHEMBL10555395 | 0.85 | SLC6A2 (0.39) | KDM1AMAOBHTR2CSLC6A4SLC6A3 | |
| SCHEMBL10552991 | 0.83 | SLC6A3 (0.42) | SLC6A3 | |
| SCHEMBL10549900 | 0.83 | KDM1A (0.36) | KDM1AKCNH2MAOBSLC6A4SLC6A3 | |
| SCHEMBL10550758 | 0.83 | ALDH1A1 (0.40) | MAOB | |
| SCHEMBL10605271 | 0.82 | SPHK1 (0.43) | SLC6A3 | |
| SCHEMBL10605267 | 0.82 | SPHK1 (0.43) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853613-A | Chiral cyclohexyl compounds | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1998-12-29 | — | — | US | disclosed |