Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470915 | 0.76 | ACE (0.61) | ACE | |
| SCHEMBL5847068 | 0.71 | ACE (0.54) | ACE | |
| SCHEMBL3154327 | 0.71 | ACE (0.54) | ACE | |
| SCHEMBL5847071 | 0.71 | ACE (0.54) | ACE | |
| SCHEMBL32676972 | 0.71 | ACE (0.54) | ACE | |
| SCHEMBL2092090 | 0.71 | ACE (0.54) | ACE | |
| SCHEMBL13971489 | 0.71 | ACE (0.54) | ACE | |
| SCHEMBL4278365 | 0.71 | ACE (0.54) | ACE | |
| SCHEMBL8028681 | 0.70 | PRCP (0.46) | OPRM1 | |
| SCHEMBL4426518 | 0.69 | HDAC3 (0.49) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736518-A | Peptide compounds of (L) amino acids and ring molecules, and therapeutical applications thereof | POLIFARMA S.P.A. (IT) | 1998-04-07 | — | — | US | disclosed |
| US-5504071-A | HYPOTENSIVE AGENTS | POLIFARMA S.P.A. (IT) | 1996-04-02 | — | — | US | disclosed |