Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12159092 | 0.79 | PRCP (0.38) | PRCPOPRM1 | |
| SCHEMBL10481214 | 0.75 | ALDH1A1 (0.39) | PRCPOPRM1 | |
| SCHEMBL8727145 | 0.70 | ACE (0.44) | OPRM1 | |
| SCHEMBL10193173 | 0.69 | MTNR1A (0.46) | — | |
| SCHEMBL13452979 | 0.69 | OPRM1 (0.49) | OPRM1SIGMAR1 | |
| SCHEMBL13155623 | 0.69 | OPRM1 (0.49) | OPRM1SIGMAR1 | |
| SCHEMBL14135549 | 0.69 | OPRM1 (0.49) | OPRM1SIGMAR1 | |
| SCHEMBL19337132 | 0.69 | MTNR1A (0.46) | — | |
| SCHEMBL13014907 | 0.68 | GPR3 (0.46) | PRCPOPRM1OPRK1 | |
| SCHEMBL11883759 | 0.67 | HTR2A (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |