Glycerin

Glycerin

SCHEMBL8727331

CC(O)C(C)(C)CO.OCC(O)CO

nearest known ligand 0.50

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
PTGS1 P23219 1/20 0.32
KCNH2 Q12809 1/20 0.32
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16326317 0.91
SCHEMBL569102 0.91
SCHEMBL16326318 0.91
Hydrogen Peroxide SCHEMBL27743972 0.88 TDP1 (0.44) LMNAALDH1A1TDP1TSHRPTGS1
Glycerin SCHEMBL5175831 0.82 LMNA (0.43) LMNAALDH1A1TDP1TSHRTHRB
Bicarbonate SCHEMBL15412275 0.81 PTGS1 (0.39) ALDH1A1TDP1PTGS1KCNH2
Glycerin SCHEMBL6265781 0.78 TDP1 (0.77) LMNAALDH1A1TDP1TSHRTHRB
Glycerin SCHEMBL204442 0.78 TDP1 (0.77) LMNAALDH1A1TDP1TSHRTHRB
Glycerin SCHEMBL6397862 0.78 TDP1 (0.77) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL10593906 0.77 TP53 (0.39) ALDH1A1TDP1PTGS1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5782244-A Method and apparatus for immobilizing the head, shoulder and torso of the human anatomy KOSTICH JEFFREY VINCENT (US) 1998-07-21 US disclosed
US-5707572-A Method for immobilizing the central nervous system of the human anatomy KOSTICH JEFFREY VINCENT (US) 1998-01-13 US disclosed
US-5454993-A Method for immobilizing the inferior portion of the human anatomy KOSTICH JEFFREY V (US) 1995-10-03 US disclosed