Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | AGL | P35573 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846021 | 1.00 | SLC18A3 (0.42) | SLC18A3ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL8727342 | 1.00 | SLC18A3 (0.42) | SLC18A3ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL12833318 | 0.82 | — | — | |
| SCHEMBL16179887 | 0.82 | — | — | |
| SCHEMBL2492659 | 0.80 | KMT2A (0.31) | — | |
| SCHEMBL6551603 | 0.79 | SLC18A3 (0.37) | SLC18A3ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL14964425 | 0.79 | SLC18A3 (0.37) | SLC18A3AGLGBA2 | |
| SCHEMBL23136777 | 0.78 | — | — | |
| SCHEMBL62606 | 0.78 | — | — | |
| SCHEMBL52490 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9717801-B2 | Glycogen-based cationic polymers | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-08-01 | — | — | US | disclosed |
| US-5824343-A | Bioerodible polymers, compositions and therapeutic method | PHARMACEUTICAL DELIVERY SYSTEMS (US) | 1998-10-20 | — | — | US | disclosed |
| US-5336505-A | Bioerodible polymers useful for the controlled release of therapeutic agents | PHARMACEUTICAL DELIVERY SYSTEMS (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0489843-A4 | BIOERODIBLE POLYMERS USEFUL FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS | — | 1992-08-12 | — | — | EP | disclosed |
| EP-0489843-A1 | BIOERODIBLE POLYMERS USEFUL FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS | PHARMACEUTICAL DELIVERY SYSTEMS, INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1991003510-A1 | BIOERODIBLE POLYMERS USEFUL FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS | PHARMACEUTICAL DELIVERY SYSTEMS, INC. (US) | 1991-03-21 | — | — | WO | disclosed |