⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727371 | 1.00 | — | — | |
| SCHEMBL8726963 | 0.94 | LMNA (0.32) | — | |
| SCHEMBL8726960 | 0.94 | LMNA (0.32) | — | |
| SCHEMBL8727395 | 0.78 | — | — | |
| SCHEMBL8727391 | 0.78 | — | — | |
| SCHEMBL16620652 | 0.78 | — | — | |
| SCHEMBL8727378 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL16620441 | 0.72 | DPP4 (0.34) | — | |
| SCHEMBL8727381 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL19031049 | 0.72 | CAMK2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5788989-A | BLOCKED END GROUPS, PROTECTING GROUPS, OCCLUSION OF DRUGS, AGROCHEMICALS, POLYPROPYLAMINE | DSM N.V. (NL) | 1998-08-04 | — | — | US | disclosed |
| EP-0741756-B1 | DENDRITIC MACROMOLECULE AND A PROCESS FOR THE PREPARATION THEREOF | DSM NV (NL) | 1998-04-22 | — | — | EP | disclosed |
| US-5698662-A | Dendritic macomolecule and a process for the preparation thereof | DSM N.V. (NL) | 1997-12-16 | — | — | US | disclosed |
| EP-0741756-A1 | DENDRITIC MACROMOLECULE AND A PROCESS FOR THE PREPARATION THEREOF | DSM N.V. (NL) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020619-A1 | DENDRITIC MACROMOLECULE AND A PROCESS FOR THE PREPARATION THEREOF | DSM N.V. (NL) | 1995-08-03 | — | — | WO | disclosed |