Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337467 | 0.84 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL20854613 | 0.79 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL27388547 | 0.79 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL29186518 | 0.77 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL30050066 | 0.77 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL1911845 | 0.77 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| Benzene SCHEMBL27999058 | 0.77 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL31138008 | 0.77 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL14483736 | 0.77 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 | |
| SCHEMBL15476234 | 0.76 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1ENPP2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776714-A | USED TO REMOVE THE BIAS CAUSED BY PRESENCE OF HEMOGLOBIN IN TEST SPECIMENS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5601994-A | Immunoassay with novel labeled drug hapten analogues | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5578457-A | QUANTITATIVE ANALYSIS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5527709-A | Immunoassays with labeled thyronine hapten analogues | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-06-18 | — | — | US | disclosed |