Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20992174 | 0.82 | TSHR (0.39) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28936397 | 0.82 | CHRM1 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL9829183 | 0.81 | CYP1A2 (0.40) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL9829180 | 0.81 | CYP1A2 (0.40) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL2163518 | 0.81 | CYP1A2 (0.40) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL20854183 | 0.80 | CHRM1 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL20854296 | 0.80 | CHRM1 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL18725609 | 0.80 | HSPD1 (0.40) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28281273 | 0.79 | CHRM1 (0.42) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Pivalate SCHEMBL5574389 | 0.78 | CHRM1 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792444-A | ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION | THE GENERAL HOSPITAL CORPORATION (US) | 1998-08-11 | — | — | US | claimed |
| US-5792444-A | ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION | THE GENERAL HOSPITAL CORPORATION (US) | 1998-08-11 | — | — | US | disclosed |