SCHEMBL87283

SCHEMBL87283

C=C(C)C(=O)Oc1ccc2sc3ccccc3c(=O)c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.62
ALDH1A1 P00352 5/20 0.62
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
KDM4E B2RXH2 3/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
PTPN7 P35236 1/20 0.46
DUSP3 P51452 1/20 0.46
PTPN12 Q05209 1/20 0.46
PTPN22 Q9Y2R2 1/20 0.46
ELANE P08246 1/20 0.46
HPGD P15428 4/20 0.42
KMT2A Q03164 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HCRTR1 O43613 2/20 0.42
MEN1 O00255 2/20 0.42
NFKB1 P19838 2/20 0.42
NFKB2 Q00653 2/20 0.42
RELA Q04206 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3233829 0.86 MAPT (0.68) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL30998124 0.86 MAPT (0.68) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL21131732 0.85 KMT2A (0.44) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL12994179 0.83 KDM4E (0.54) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL12576351 0.81 MAPT (0.52) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL30998139 0.81 MAPT (0.61) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL85778 0.81 MAPT (0.61) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL10962265 0.81 MAPT (0.69) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL19647434 0.81 MAPT (0.60) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL11994247 0.80 MAPT (0.59) MAPTALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3083804-B1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES BOREALIS AG (AT) 2017-11-29 EP disclosed
US-20160312007-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES BOREALIS AG (AT) 2016-10-27 US disclosed
US-20160312007-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES BOREALIS AG (AT) 2016-10-27 US disclosed
WO-2015090604-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES BOREALIS AG (AT) 2015-06-25 WO disclosed
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 MAPT 2087/4885ALDH1A1 440/4885NPC1 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.