SCHEMBL85778

SCHEMBL85778

C=CC(=O)Oc1ccc2sc3ccccc3c(=O)c2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
ALDH1A1 P00352 5/20 0.61
KDM4E B2RXH2 3/20 0.61
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
PTPN7 P35236 1/20 0.45
DUSP3 P51452 1/20 0.45
PTPN12 Q05209 1/20 0.45
PTPN22 Q9Y2R2 1/20 0.45
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
HPGD P15428 3/20 0.43
HCRTR1 O43613 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30998139 1.00 MAPT (0.61) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL16708721 0.93 KDM4E (0.49) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL31120514 0.92 ALDH1A1 (0.50) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL3790672 0.92 ALDH1A1 (0.50) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL11994247 0.88 MAPT (0.59) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL86424 0.86 MAPT (0.45) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL3791223 0.85 MAPT (0.57) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL11994245 0.84 THRB (0.54) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL31271888 0.84 THRB (0.54) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL25027901 0.83 KDM4E (0.46) MAPTALDH1A1KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417318-A1 METHOD FOR SPRAY COATING A SURFACE ATTACHED HYDROGEL STRECK LLC (US) 2024-12-19 US claimed
EP-4419605-A1 METHOD FOR SPRAY COATING A SURFACE ATTACHED HYDROGEL Streck LLC (US) 2024-08-28 EP claimed
WO-2023069566-A1 METHOD FOR SPRAY COATING A SURFACE ATTACHED HYDROGEL STRECK, INC. (US) 2023-04-27 WO claimed
CN-114539196-B Single-component hydrogen abstraction type photoinitiator capable of inverse photo-crosslinking and preparation method and application thereof 广州鹿山新材料股份有限公司 2023-03-21 CN claimed
CN-114539196-A Single-component hydrogen abstraction type photoinitiator capable of inverse photo-crosslinking and preparation method and application thereof 广州鹿山新材料股份有限公司 2022-05-27 CN claimed
US-20240417318-A1 METHOD FOR SPRAY COATING A SURFACE ATTACHED HYDROGEL STRECK LLC (US) 2024-12-19 US disclosed
WO-2024247999-A1 ADHESIVE AGENT COMPOSITION, ADHESIVE AGENT, AND ADHESIVE SHEET 三菱ケミカル株式会社 2024-12-05 WO disclosed
CN-118732123-A Optical laminate 住友化学株式会社 2024-10-01 CN disclosed
EP-4419605-A1 METHOD FOR SPRAY COATING A SURFACE ATTACHED HYDROGEL Streck LLC (US) 2024-08-28 EP disclosed
US-20230159706-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS UNIVERSITE DE HAUTE ALSACE (FR) 2023-05-25 US disclosed
WO-2023069566-A1 METHOD FOR SPRAY COATING A SURFACE ATTACHED HYDROGEL STRECK, INC. (US) 2023-04-27 WO disclosed
US-11629233-B2 Free-radical photoinitiators and uses of same in silicone compositions ELKEM SILICONES FRANCE SAS (FR) 2023-04-18 US disclosed
EP-2065362-A1 Preparation method of copolymerizable photoinitiators Agfa Graphics N.V. (BE) 2009-06-03 EP disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-6296986-B1 MULTIFUNCTIONAL CORE WITH REACTIVE GROUPS AND PHOTOINITIATORS COATES BROTHERS PLC (GB) 2001-10-02 US disclosed
EP-0859797-A1 PHOTOINITIATOR Coates Brothers PLC (GB) 1998-08-26 EP disclosed
WO-1997017378-A9 PHOTOINITIATOR 1997-10-30 WO disclosed
WO-1997017378-A1 PHOTOINITIATOR COATES BROTHERS PLC (GB) 1997-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 MAPT 2087/4885ALDH1A1 440/4885KDM4E 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.