Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.71 |
| ▸ | RARB | P10826 | 3/20 | 0.67 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | THRA | P10827 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053280 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1019300 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL5206359 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL2387345 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL2399489 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1022325 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9161795 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10045771 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL4209056 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1023839 | 0.98 | TP53 (0.70) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |