Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.71 |
| ▸ | RARB | P10826 | 3/20 | 0.67 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | THRA | P10827 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053280 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1019300 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL5206359 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL2387345 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1022325 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8728342 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9161795 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10045771 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL4209056 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1023839 | 0.98 | TP53 (0.70) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539389-B1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA INC (US) | 2017-12-20 | — | — | EP | disclosed |
| US-20170258825-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. | 2017-09-14 | — | — | US | disclosed |
| US-9655920-B2 | Amine polymers for use as bile acid sequestrants | RELYPSA, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20140356316-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2014-12-04 | — | — | US | disclosed |
| EP-2539389-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | Relypsa, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106548-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| EP-0586263-A1 | A liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1994-03-09 | — | — | EP | disclosed |
| EP-0331367-B1 | Liquid crystal compounds having fluoroalkyl radical | SHOWA SHELL SEKIYU (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5051527-A | Liquid crystal compounds having fluoroalkyl radical | SHOWA SHELL SEKIYU K.K. (JP) | 1991-09-24 | — | — | US | disclosed |
| EP-0240184-B1 | ALPHA-METHYLCINNAMIC ACID ESTER DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0331367-A2 | Liquid crystal compounds having fluoroalkyl radical | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |
| US-4751018-A | DISCOLORATION INHIBITION | MITSUBISHI RAYON COMPANY LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0240184-A2 | Alpha-Methylcinnamic acid ester derivative and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4251545-A | Fungicidal process using 1-(alkoxyaroyl)guanidines | GAF CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258825-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | NR1H4, SLC10A2, SLC10A1 | TP53 4225/4885TSHR 3114/4885PLA2G4B 2970/4885 |
| US-20140356316-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | NR1H4, SLC10A2, SLC10A1 | TP53 4225/4885TSHR 3114/4885PLA2G4B 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.