SCHEMBL8728394

SCHEMBL8728394

CC=Cc1ccc(-c2ccc(COCCCC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
NAAA Q02083 1/20 0.38
AHR P35869 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732403 1.00 CYP3A4 (0.41) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8732404 1.00 CYP3A4 (0.41) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8728393 1.00 CYP3A4 (0.41) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8727692 0.95 L3MBTL1 (0.41) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8725033 0.95 L3MBTL1 (0.41) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8727689 0.95 L3MBTL1 (0.41) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8725030 0.95 L3MBTL1 (0.41) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8732753 0.90 KDM4E (0.39) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8730650 0.90 KDM4E (0.39) CYP3A4LMNAALDH1A1TP53TSHR
SCHEMBL8732755 0.90 KDM4E (0.39) CYP3A4LMNAALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed