Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728663 | 1.00 | GAA (0.67) | GAANPY5RKMT2AMEN1ALDH1A1 | |
| SCHEMBL16147201 | 1.00 | GAA (0.67) | GAANPY5RKMT2AMEN1ALDH1A1 | |
| SCHEMBL25409408 | 0.85 | GAA (0.80) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL5804993 | 0.85 | GAA (0.80) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL4992458 | 0.85 | GAA (0.80) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL8153290 | 0.85 | NPY5R (0.78) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL9067935 | 0.83 | GAA (0.60) | GAANPY5RKMT2AMEN1ALDH1A1 | |
| SCHEMBL6223855 | 0.81 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL3447214 | 0.81 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL3447213 | 0.81 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751927-A4 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INST OF TECHN (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0751927-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025714-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1995-09-28 | — | — | WO | disclosed |