Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734785 | 0.81 | ESR2 (0.48) | KMT2ANPC1RAB9AALDH1A1ESR2 | |
| SCHEMBL8733650 | 0.80 | ESR2 (0.47) | KMT2AMEN1HTTNPC1RAB9A | |
| SCHEMBL13894950 | 0.79 | KMT2A (0.60) | KMT2AMEN1L3MBTL1HTTMLYCD | |
| SCHEMBL14219225 | 0.76 | KMT2A (0.74) | KMT2AMEN1L3MBTL1HTTNPC1 | |
| SCHEMBL4064581 | 0.76 | KMT2A (1.00) | KMT2AMEN1L3MBTL1HTTNPC1 | |
| SCHEMBL3105476 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1L3MBTL1HTTMLYCD | |
| SCHEMBL7374914 | 0.74 | KMT2A (0.72) | KMT2AMEN1L3MBTL1HTTMLYCD | |
| SCHEMBL10044266 | 0.74 | KMT2A (0.57) | KMT2AMEN1L3MBTL1HTTMLYCD | |
| SCHEMBL3366949 | 0.73 | KMT2A (0.70) | KMT2AMEN1L3MBTL1HTTMLYCD | |
| SCHEMBL8188967 | 0.73 | KMT2A (0.70) | KMT2AMEN1L3MBTL1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751927-A4 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INST OF TECHN (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0751927-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025714-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1995-09-28 | — | — | WO | disclosed |