Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777973 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL626087 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL9679556 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL8728605 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL10466262 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL3326982 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL384635 | 0.78 | CYP1A2 (0.50) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL18912100 | 0.78 | CYP1A2 (0.53) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL7775829 | 0.78 | CYP1A2 (0.58) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL4078018 | 0.77 | CYP1A2 (0.56) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |