Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820285 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2AGTR2NPC1RAB9ACYP2C19 | |
| SCHEMBL23485195 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2AGTR2NPC1RAB9ACYP2C19 | |
| SCHEMBL819239 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2AGTR2NPC1RAB9ACYP2C19 | |
| SCHEMBL7659903 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2AGTR2NPC1RAB9ACYP2C19 | |
| SCHEMBL5740609 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2AGTR2NPC1RAB9ACYP2C19 | |
| SCHEMBL29302842 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2AGTR2NPC1RAB9ACYP2C19 | |
| SCHEMBL29302825 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2AGTR2NPC1RAB9ACYP2C19 | |
| SCHEMBL7389859 | 0.82 | FABP5 (0.41) | AGTR2 | |
| SCHEMBL4446424 | 0.82 | FABP5 (0.41) | AGTR2 | |
| SCHEMBL21315767 | 0.82 | FABP5 (0.41) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736518-A | Peptide compounds of (L) amino acids and ring molecules, and therapeutical applications thereof | POLIFARMA S.P.A. (IT) | 1998-04-07 | — | — | US | disclosed |