SCHEMBL8728838

SCHEMBL8728838

C=COC1(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8725777 1.00
SCHEMBL726912 0.97
SCHEMBL2871185 0.67
SCHEMBL4642583 0.66 TSHR (0.33)
SCHEMBL3813864 0.66 TSHR (0.33)
SCHEMBL4799755 0.65
SCHEMBL9935587 0.62 MEN1 (0.31)
SCHEMBL4642632 0.61 TSHR (0.34)
SCHEMBL4810647 0.61
SCHEMBL31314317 0.60 MEN1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0613485-B1 THERMOPLASTIC FLUOROCOPOLYMERS, AND METHOD OF PREPARING FLUOROMONOMER FOR USE IN THE MANUFACTURE OF THE FLUOROCOPOLYMER BAYER AG (DE) 1998-03-25 EP disclosed
US-5426165-A Heat resistance, dimensional stability BAYER AKTIENGESELLSCHAFT (DE) 1995-06-20 US disclosed
EP-0613485-A1 THERMOPLASTIC FLUOROCOPOLYMERS, AND METHOD OF PREPARING FLUOROMONOMER FOR USE IN THE MANUFACTURE OF THE FLUOROCOPOLYMER BAYER AG (DE) 1994-09-07 EP disclosed
WO-1993010160-A1 NEW THERMOPLASTIC FLUOROCOPOLYMERS, AND FLUOROMONOMERS FOR USE IN THEIR MANUFACTURE BAYER AKTIENGESELLSCHAFT (DE) 1993-05-27 WO disclosed