SCHEMBL3813864

SCHEMBL3813864

C=CC(=O)OC1(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.33
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642583 1.00 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4642632 0.98 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5137465 0.82 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8610647 0.80 KEAP1 (0.33)
SCHEMBL4328621 0.78 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL13913343 0.77
SCHEMBL13913336 0.77
SCHEMBL4816348 0.76
SCHEMBL4323604 0.73 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL137442 0.73 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746313-B Polyester resin, powder coating and preparation method and application thereof 擎天材料科技有限公司 2024-02-06 CN claimed
CN-115746313-A Polyester resin, powder coating, and preparation method and application thereof 擎天材料科技有限公司 2023-03-07 CN claimed
CN-111073435-B High-hardness anti-corrosion water-based baking coating based on liquid crystal modified acrylic resin 安徽广成新材料科技有限公司 2022-04-08 CN claimed
CN-111073435-A High-hardness anti-corrosion water-based baking coating based on liquid crystal modified acrylic resin 王新民 2020-04-28 CN claimed
CN-107138056-A One kind is used for N2/CH4The gas separation membrane of separation 天津工业大学 2017-09-08 CN claimed
EP-1287047-B1 PHOTO-POLYMERS AND USE THEREOF TERAHERTZ PHOTONICS LTD (GB) 2008-08-13 EP claimed
US-6861205-B2 Three dimensional microstructures and method of making BATTELLE MEMORIAL INSTITUTE (US) 2005-03-01 US claimed
US-20030148222-A1 Three dimensional microstructures and method of making BATTELLE MEMORIAL INSTITUTE 2003-08-07 US claimed
US-20030114619-A1 Photo-polymers and use thereof TERAHERTZ PHOTONICS LIMITED (GB) 2003-06-19 US claimed
EP-1287047-A1 PHOTO-POLYMERS AND USE THEREOF TeraHertz Photonics Limited (GB) 2003-03-05 EP claimed
US-5863298-A USING PRESSURIZED CARBON DIOXIDE WITH FLUORINATED HYDROCARBON IN CONTACT WITH YARN BATTELLE MEMORIAL INSTITUTE (US) 1999-01-26 US claimed
WO-1997033033-A1 METHOD FOR SIZING AND DESIZING YARNS WITH LIQUID AND SUPERCRITICAL CARBON DIOXIDE SOLVENT BATTELLE MEMORIAL INSTITUTE (US) 1997-09-12 WO claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
EP-0493320-B1 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA GEIGY AG (CH) 1996-07-31 EP claimed
EP-0406161-B1 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA GEIGY AG (CH) 1995-02-22 EP claimed
EP-0493320-A2 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA-GEIGY AG (CH) 1992-07-01 EP claimed
US-5115056-A FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF CIBA-GEIGY CORPORATION (US) 1992-05-19 US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
EP-0406161-A2 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1991-01-02 EP claimed