Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.60 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.46 |
| ▸ | WNT3A | P56704 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30257325 | 0.87 | CNR1 (0.63) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL8728950 | 0.87 | CNR1 (0.63) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL9040996 | 0.85 | CNR1 (0.62) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL9144238 | 0.84 | CNR1 (0.60) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL12450809 | 0.83 | CNR1 (0.56) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| Lithium Ion SCHEMBL9040989 | 0.83 | CNR1 (0.59) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL13875364 | 0.81 | CNR1 (0.58) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL6811997 | 0.81 | CNR1 (0.54) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL12450018 | 0.80 | CNR1 (0.56) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL6812882 | 0.80 | CNR1 (0.56) | CNR1SRD5A1SRD5A2CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767139-A | SKIN DISORDERS; ALOPECIA; PROSTATE CANCER | PFIZER, INC. (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0628040-B1 | INDOLE DERIVATIVES AS STEROID 5 ALPHA-REDUCTASE INHIBITORS | PFIZER LTD (GB) | 1998-03-25 | — | — | EP | disclosed |
| EP-0628040-A1 | INDOLE DERIVATIVES AS STEROID 5 ALPHA-REDUCTASE INHIBITORS | Pfizer Limited (GB) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017014-A1 | INDOLE DERIVATIVES AS STEROID 5 ALPHA-REDUCTASE INHIBITORS | PFIZER LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |