Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.54 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595558 | 0.86 | CNR1 (0.54) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL8728849 | 0.81 | CNR1 (0.60) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL30257325 | 0.81 | CNR1 (0.63) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL8728950 | 0.81 | CNR1 (0.63) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL9040996 | 0.79 | CNR1 (0.62) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL9144238 | 0.78 | CNR1 (0.60) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL4694766 | 0.77 | CNR1 (0.56) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL6812882 | 0.77 | CNR1 (0.56) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| SCHEMBL12450809 | 0.77 | CNR1 (0.56) | CNR1SRD5A1SRD5A2CTNNB1WNT3A | |
| Lithium Ion SCHEMBL9040989 | 0.77 | CNR1 (0.59) | CNR1SRD5A1SRD5A2CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828513-B1 | COMBINATIONS FOR THE TREATMENT OF PARKINSONISM CONTAINING SELECTIVE NMDA ANTAGONISTS | PFIZER (US) | 2004-01-21 | — | — | EP | disclosed |
| US-6258827-B1 | HYDROXYAROMATIC HETEROCYCLIC ALKANOLS AND LEVODOPA | PFIZER INC. | 2001-07-10 | — | — | US | disclosed |
| US-6046213-A | Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydroxyphenyl)-2-(piperidinyl-1)-alkanol derivatives | PFIZER INC. (US) | 2000-04-04 | — | — | US | disclosed |
| EP-0828513-A2 | COMBINATIONS FOR THE TREATMENT OF PARKINSONISM CONTAINING SELECTIVE NMDA ANTAGONISTS | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037226-A2 | COMBINATIONS FOR THE TREATMENT OF PARKINSONISM CONTAINING SELECTIVE NMDA ANTAGONISTS | PFIZER INC. (US) | 1996-11-28 | — | — | WO | disclosed |