⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817646 | 0.72 | — | — | |
| SCHEMBL8436669 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL2960702 | 0.66 | PBRM1 (0.33) | — | |
| SCHEMBL2962283 | 0.62 | MAPK1 (0.39) | — | |
| SCHEMBL2960706 | 0.60 | PBRM1 (0.46) | — | |
| SCHEMBL2975608 | 0.59 | MEN1 (0.36) | — | |
| SCHEMBL12191049 | 0.57 | ESR1 (0.54) | — | |
| SCHEMBL8161345 | 0.57 | TSHR (0.50) | — | |
| SCHEMBL6756342 | 0.57 | TSHR (0.40) | — | |
| SCHEMBL16708588 | 0.56 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728773-B1 | Catalysts for olefin polymerization and a process for preparing olefin polymers therewith | MITSUBISHI CHEM CORP (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0693502-B1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEM CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5594081-A | METALLOCENES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0728773-A1 | Catalysts for olefin polymerization and a process for preparing olefin polymers therewith | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0693502-A1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |